Author
Children's Hospital of PhiladelphiaORCID 0000-0003-2985-9954Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Hoang Anh T. Phan, Soomin Eom, Daniel Hwang…·Nikolaos G. Sgourakis
The paper introduces VLP-Open HLA nanoparticles for high-throughput T cell screening, enabling efficient peptide exchange and antigen-specific T cell activation.
Wyatt Blackson, Ean L. Small, Shirley M. Sun…·Nikolaos G. Sgourakis
The paper develops a system to create binders compatible across HLA allotypes, validated against clinically relevant antigens and demonstrated in CAR T cells.
Photis Rotsides, Omkar Shinde, Julia N. Danon, Nikolaos G. Sgourakis
This paper develops a stabilized MR1 variant, SMART-MR1, that preserves native-like ligand presentation and TCR recognition while enabling biochemical and structural studies.