Natalia Korotkova

CflP couples magnesium availability to CovS signaling in Group B Streptococcus

This study identifies CflP as an accessory regulator of CovS in GBS, linking magnesium availability to virulence gene repression and immune cell cytotoxicity.

Enterococcus faecalis autolysin, EpaU, binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling

This study identifies EpaU as an autolysin that binds the enterococcal polysaccharide antigen and modulates c-di-AMP signaling, affecting antibiotic resistance and cell turgor in Enterococcus faecalis.

Natural variation of the streptococcal Group A carbohydrate biosynthesis genes impacts host-pathogen interaction

The paper identifies genetic variation in the gacA-L cluster of S. pyogenes and shows that inactivating mutations in gacH reduce GroP decoration, affecting host-pathogen interactions.

A conserved glycan motif overcomes antigenic variation inducing broadly reactive antibodies against the zoonotic pathogen Streptococcus suis

This study identifies a conserved glycan motif in Streptococcus suis that elicits broadly reactive antibodies, suggesting it as a target for next-generation vaccines.

Glycosylation of serine/threonine-rich intrinsically disordered regions of membrane-associated proteins in streptococci

The paper identifies glycosylation of serine/threonine-rich IDRs in streptococcal membrane proteins and shows its role in biofilm formation.

Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide

This study identifies the structure and biosynthesis mechanism of Streptococcus mutans cell wall polysaccharide, revealing key modifications and their roles in bacterial morphology and biofilm formation.