Enforced E-selectin ligand installation enhances homing and efficacy of adoptively transferred T cells
Yingqin Hou, Jinfeng Ye, Ke Qin, Leigh-Ann Cui, Shereen Chung, Digantkumar Gopaldas Chapla, Wenjian Wang, Yujie Shi, Mingkuan Chen, Kelley W. Moremen, Robert Sackstein, Peng Wu
This study shows that exofucosylation of T cells enhances their homing and therapeutic efficacy in treating solid tumors and metastases.
bioRxiv · Jan 12, 2025 · PreprintCancer Biology