Leizhi Shi

Tracheal terminal cells of Drosophila are immune privileged to maintain their Foxo-dependent structural plasticity

The paper shows that Drosophila tracheal terminal cells are immune-privileged to maintain Foxo-dependent structural plasticity, as immune activation leads to cell death and structural damage.

Preconception e-nicotine impairs airway development and progenitor proliferation across generations in Drosophila Melanogaster

This study shows that preconception e-nicotine exposure in Drosophila leads to airway developmental defects and physiological abnormalities that persist across generations.

JNK integrates immune and stress signals to balance apoptosis and proliferation in airway progenitors

This study identifies JNK as a key integrator of immune and stress signals in airway progenitors, balancing apoptosis and proliferation to maintain tissue homeostasis during inflammation.

A Goldilocks principle of JAK/STAT signaling governs airway epithelial homeostasis and stress adaptation in Drosophila

This study shows that JAK/STAT signaling in Drosophila airway epithelia must be balanced to maintain homeostasis and stress adaptation, with both insufficient and excessive activity causing pathology.