Author

Letizia Pizzini

Candiolo Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alberto PuliafitoiD· 2 shared Andrea BertottiiD· 2 shared Elena GrassiiD· 2 shared Federica GalvagnoiD· 2 shared Luca PrimoiD· 2 shared Sabrina Johanna FletcheriD· 2 shared Andrea PirasiD· 1 shared Antonio CelaniiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersCancer Biology

Alberto PuliafitoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Inference of lineage hierarchies, growth and drug response mechanisms in cancer cell populations without tracking

Andrea Piras, Federica Galvagno, Letizia Pizzini, Matteo Nunziante, Sabrina Johanna Fletcher, Elena Grassi, Andrea Bertotti, Luca Primo, Antonio Celani, Alberto Puliafito

This study introduces a method to infer lineage hierarchies and drug response mechanisms in cancer cell populations without single-cell tracking, demonstrating its effectiveness through simulations and experiments.

Cell Reports Methods · Aug 17, 2026Peer-reviewedCancer Biology

TGF-β1-induced differentiation enhances chemotherapy response in metastatic colorectal cancer organoids

Sabrina Johanna Fletcher, Letizia Pizzini, Irene Catalano, Miriam Palmiero, Federica Galvagno, Sofia Borgato, Elena Grassi, Andrea Bertotti, Luca Primo, Livio Trusolino, Alberto Puliafito

This study shows that TGF-β1-induced differentiation in colorectal cancer organoids enhances chemotherapy response by reducing clonogenic capacity and increasing oxaliplatin cytotoxicity.

bioRxiv · Jun 8, 2026 · PreprintCancer Biology

Topic Modeling analysis of the Allen Human Brain Atlas

Letizia Pizzini, Filippo Valle, Matteo Osella, Michele Caselle

This paper introduces a hierarchical Stochastic Block Modeling approach to identify universal gene expression patterns in the human brain using the Allen Human Brain Atlas dataset.

Scientific Reports · Feb 26, 2025Peer-reviewedBiophysics