Cancer BiologybioRxivPreprint
TGF-β1-induced differentiation enhances chemotherapy response in metastatic colorectal cancer organoids
Sabrina Johanna Fletcher, Letizia Pizzini, Irene Catalano…·Alberto Puliafito
This study shows that TGF-β1-induced differentiation in colorectal cancer organoids enhances chemotherapy response by reducing clonogenic capacity and increasing oxaliplatin cytotoxicity.