Evaluating Spike Antigenicity across Endemic Human Coronavirus Models using Flow Virometry
Jonathan Burnie, Caroline Ouano, Victor Luo, Christian K. O. Dzuvor, Taiya Miller, Giancarlo Ospina, Nikhila S. Tanneti, Li Hui Tan, Donald J. Hamel, Catherine Hammond, Hannah R. Matthews, Lamount R. Evanson, Jeswin Joseph, Sydney P. Moak, Phyllis J Kanki, , Kizzmekia S. Corbett
This study uses flow virometry to analyze spike antigenicity of endemic human coronaviruses, revealing cell line-dependent differences and heterogeneity not captured by bulk assays.
bioRxiv · May 29, 2026 · PreprintMicrobiology