Author

Sydney P. Moak

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Christian K. O. DzuvoriD· 4 shared Kizzmekia S. CorbettiD· 4 shared Jeswin JosephiD· 3 shared Abigail E. DzordzormeiD· 2 shared Abigail Thomas· 2 shared Catherine Hammond· 2 shared Lamount R. EvansoniD· 2 shared Lindsay R. McManusiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMicrobiology

Christian K. O. DzuvorORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evaluating Spike Antigenicity across Endemic Human Coronavirus Models using Flow Virometry

Jonathan Burnie, Caroline Ouano, Victor Luo, Christian K. O. Dzuvor, Taiya Miller, Giancarlo Ospina, Nikhila S. Tanneti, Li Hui Tan, Donald J. Hamel, Catherine Hammond, Hannah R. Matthews, Lamount R. Evanson, Jeswin Joseph, Sydney P. Moak, Phyllis J Kanki, , Kizzmekia S. Corbett

This study uses flow virometry to analyze spike antigenicity of endemic human coronaviruses, revealing cell line-dependent differences and heterogeneity not captured by bulk assays.

bioRxiv · May 29, 2026 · PreprintMicrobiology

Unconventional linkers facilitate potent stabilized coronavirus stem antibody responses following nanoparticle vaccination

Christian K. O. Dzuvor, Sydney P. Moak, Lindsay R. McManus, Abigail E. Dzordzorme, Lamount R. Evanson, Tae‐Woo Kim, Abigail Thomas, Olayimika Adeyemi, Valerie Foley, Aditi Limaye, Ryan P. McNamara, Kizzmekia S. Corbett

This paper designs and evaluates nanoparticle vaccines with optimized linkers to enhance cross-reactive antibody responses against coronaviruses and other viral families.

bioRxiv · Nov 19, 2025 · PreprintBioengineering

Structural Definition of Neutralizing Epitopes within and around the HKU1 Receptor-binding Site Reveals Cell Context-Dependent Neutralization

Jeswin Joseph, Lingshu Wang, Sheena Vasquez, Chia-Ming Su, Daniel Wrapp, Osnat Rosen, Olubukola M. Abiona, Christian K. O. Dzuvor, Robert N. Kirchdoerfer, Sydney P. Moak, Timothy Patrick Sheahan, Catherine Hammond, Wei Shi, Wing‐Pui Kong, Yi Zhang, , Kizzmekia S. Corbett

This study identifies mAbs targeting HCoV-HKU1 spike protein and shows that receptor-binding site recognition alone does not predict neutralization in primary cells.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology

Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles Elicit Broad Antibody Responses

Christian K. O. Dzuvor, Sydney P. Moak, Lindsay R. McManus, Abigail Thomas, Abigail E. Dzordzorme, Tae‐Woo Kim, Jeswin Joseph, Valerie Foley, Ingelise J. Gordon, Laura Novik, LaSonji A. Holman, Lesia K. Dropulic, Ryan P. McNamara, Kizzmekia S. Corbett

The paper designs multiclade coronavirus spike immunodominant domain nanoparticles that elicit broad antibody responses against multiple EhCoVs and SARS-CoV-2 variants in mice.

bioRxiv · Oct 1, 2025 · PreprintBioengineering