Author

Liangzhen Hou

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kun WangiD· 2 shared Xionglei HeiD· 2 shared Zhaolian LuiD· 2 shared Zheng HuiD· 2 shared Christina N. CurtisiD· 1 shared Da ZhouiD· 1 shared Duo XieiD· 1 shared Herrero-Herrero JiiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Kun WangORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Testing the plasticity-first theory of tumor evolution with spatiotemporal lineage tracing

Jinhua Yang, Liangzhen Hou, Xue Wang, Ningxia Zhang, Yifei Bian, Zhaolian Lu, Yanxu Chen, Duo Xie, Yongting Fang, Kun Wang, Ruijie Wan, Yujuan Jin, Yuan Chen, Xinlei Cai, Xiaojing Hu, , Herrero-Herrero Ji

This study uses lineage tracing and single-cell analysis to show tumor plasticity precedes stable immune evasion, with AP-1 regulating EMT stabilization during immunotherapy.

bioRxiv · Aug 6, 2025 · PreprintCancer Biology

Cell division history encodes directional information of fate transitions

Kun Wang, Liangzhen Hou, Zhaolian Lu, Xin Wang, Zhike Zi, Weiwei Zhai, Xionglei He, Christina N. Curtis, Da Zhou, Zheng Hu

The paper introduces PhyloVelo, a method that uses monotonically expressed genes to reconstruct cell fate transitions, outperforming existing approaches in embryo development and tumor evolution analysis.

bioRxiv · Oct 6, 2022 · PreprintGenomics