Author

Lilija Brant

University of Cologne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Argyris PapantonisiD· 3 shared Eduardo Gade GusmaoiD· 2 shared Julia FranzeniD· 2 shared Miloš NikolićiD· 2 shared Wolfgang WagneriD· 2 shared Alina Ostrowska· 1 shared Anne Zirkel· 1 shared Anthony Dick HoiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersGenomics

Argyris PapantonisORCID

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3 papers

Recent·Most cited

Epigenetic drift during long-term culture of cells in vitro

Julia Franzen, Theodoros Georgomanolis, Anton Selich, Chao‐Chung Kuo, Reinhard J. Stöger, Lilija Brant, Melita Sara Mulabdić, Eduardo Fernández‐Rebollo, Clara Grezella, Alina Ostrowska, Matthias Begemann, Miloš Nikolić, Björn Rath, Anthony Dick Ho, Michael Rothe, , Wolfgang Wagner

This study identifies DNA methylation changes during long-term cell culture that resemble epigenetic drift, linked to chromatin conformation changes.

Communications Biology · May 19, 2021Peer-reviewedGenomics

Retrieving high-resolution chromatin interactionsand decoding enhancer regulatory potential in silico

Eduardo Gade Gusmao, Athanasia Mizi, Lilija Brant, Argyris Papantonis

Bloom is a method for analyzing 3C-type data that retrieves hidden interaction patterns and detects enhancer-promoter interactions with a frequency score, enabling the decoding of regulatory landscapes.

bioRxiv · Nov 10, 2020 · PreprintBioinformatics

Topological Demarcation By HMGB2 Is Disrupted Early Upon Senescence Entry Across Cell Types And Induces CTCF Clustering

Anne Zirkel, Miloš Nikolić, Konstantinos Sofiadis, Jan‐Philipp Mallm, Lilija Brant, Christian Becker, Janine Altmüller, Julia Franzen, Mirjam Koker, Eduardo Gade Gusmao, Ivan G. Costa, Roland Tillmann Ullrich, Wolfgang Wagner, Peter Nürnberg, Karsten Rippe, Argyris Papantonis

The paper identifies HMGB2 loss as an early event in senescence that disrupts chromatin organization by inducing CTCF clustering across multiple human cell types.

bioRxiv · Apr 14, 2017 · PreprintGenomics