Christian Becker

Chromosome-level genome assembly and annotation of the parthenogenetic nematode Acrobeloides nanus

This paper presents a chromosome-level genome assembly of Acrobeloides nanus, revealing genomic features and adaptations related to parthenogenesis and desiccation resistance.

Genomes of ancient asexual mites appear streamlined in their architecture

This study compares the genomes of ancient asexual and sexual oribatid mites, finding that asexual species have streamlined genomes with fewer novel genes compared to their sexual relatives.

Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations

The paper imputes structural variants using a multi-ancestry long-read sequencing panel and identifies disease associations in large-scale datasets.

RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis

The paper shows RNA polymerase II is necessary for spatial chromatin reorganization after mitosis, as demonstrated by Hi-C and in silico modeling.

Topological Demarcation By HMGB2 Is Disrupted Early Upon Senescence Entry Across Cell Types And Induces CTCF Clustering

The paper identifies HMGB2 loss as an early event in senescence that disrupts chromatin organization by inducing CTCF clustering across multiple human cell types.