Peter A. C. Wing

Hypoxia inducible factors regulate Pneumovirus replication by enhancing innate immune sensing

This study shows that HIF activation limits pneumovirus replication by enhancing innate immune sensing and reducing viral RNA methylation.

PreS1-decorated recombinant adenovirus encoding HBV antigens generates neutralizing humoral and cellular immunity

This study develops a vaccine using PreS1-decorated adenovirus that induces neutralizing antibodies and T-cell responses against HBV and HDV.

obABPP-HT*: A Precision-Engineered Activity Proteomics Pipeline for the Streamlined Discovery of Deubiquitinase Inhibitors

This paper introduces a high-throughput activity proteomics pipeline for discovering deubiquitinase inhibitors, identifying potent and selective inhibitors with minimal optimization.

Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome

This paper introduces BACS, a method for single-base resolution pseudouridine quantification, and identifies {Psi} sites in human RNA and viral transcripts.

Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression

This study shows that hypoxia inducible factors (HIFs) suppress RSV infection by reducing nucleolin expression and inhibiting viral replication and inflammation.