Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet
Domenico Iuso, I. Garcia-Saez, Yohann Couté, Yoshiki Yamaryo‐Botté, Elisabetta Boeri Erba, Annie Adrait, Nour Zeaiter, Małgorzata Tokarska-Schlattner, Zuzana Macek Jílková, Fayçal Boussouar, Sophie Barral, Luca Signor, Karine Couturier, Azadeh Hajmirza, Florent Chuffart, , Saadi Khochbin
This study shows that NME1/2 regulate liver response to high-fat diet by repressing de novo lipogenesis and activating protective gene expression through histone acetylation.
Science Advances · Sep 6, 2023Peer-reviewedMolecular Biology