Denis Puthier

ATAD2 mediates chromatin-bound histone chaperone turnover

This study shows ATAD2 regulates chromatin-bound histone chaperone turnover, affecting H3.3 localization and gene transcription during spermatogenesis.

SciGeneX: Enhancing transcriptional analysis through gene module detection in single-cell and spatial transcriptomics data.

SciGeneX detects gene modules in single-cell and spatial transcriptomics data to reveal cell populations, outperforming existing methods and uncovering rare cell types in human thymus data.

Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet

This study shows that NME1/2 regulate liver response to high-fat diet by repressing de novo lipogenesis and activating protective gene expression through histone acetylation.