Author
Centre Hospitalier Universitaire Sainte-Justine
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Elizabeth Elder, Anthony Lemieux, Lisa‐Marie Legault…·Serge McGraw
This paper investigates whether rescuing DNMT1 activity can reverse its loss in mouse embryonic stem cells, finding only partial reversal with lasting effects on epigenetic landscapes and cellular function.
Lisa‐Marie Legault, Thomas Dupas, Mélanie Breton‐Larrivée…·Serge McGraw
This study examines sex-specific DNA methylation and gene expression changes in mouse placentas after early preimplantation alcohol exposure, finding significant differences in molecular profiles between male and female placentas.
Lisa‐Marie Legault, Mélanie Breton‐Larrivée, Alexandra Langford‐Avelar…·Serge McGraw
This study identifies sex-based differences in DNA methylation and gene expression in late-gestation mouse placentas, revealing distinct patterns on the X chromosome and autosomes.
Lisa‐Marie Legault, Karine Doiron, Mélanie Breton‐Larrivée…·Serge McGraw
This study shows that pre-implantation alcohol exposure causes sex-specific DNA methylation errors in fetal mouse forebrains, potentially contributing to FASD-related neurodevelopmental issues.
Lisa‐Marie Legault, Karine Doiron, A Lemieux…·Serge McGraw
The paper investigates DNA methylation asymmetry between mouse placenta and embryo, identifying DMR subtypes and the role of DNMT3B and DNMT3A in establishing and maintaining these patterns.