Alexandra Langford‐Avelar

This study shows that 3D spheroid culture of NSCLC cells undergoes time-dependent chromatin and transcriptomic changes that improve drug response prediction and correlation with tumors.

This study examines sex-specific DNA methylation and gene expression changes in mouse placentas after early preimplantation alcohol exposure, finding significant differences in molecular profiles between male and female placentas.

This study identifies sex-based differences in DNA methylation and gene expression in late-gestation mouse placentas, revealing distinct patterns on the X chromosome and autosomes.

This study shows that pre-implantation alcohol exposure causes sex-specific DNA methylation errors in fetal mouse forebrains, potentially contributing to FASD-related neurodevelopmental issues.

This study validates two genome-wide polygenic risk scores for coronary artery disease in French Canadians, showing good performance for prevalent CAD but limited utility for incident and recurrent CAD.