Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation
Yifan Wu, Kunhua Qin, Yi Xu, Shreya Rajhans, Truong Vo, Kevin M Lopez, Jun Liu, Michael H Nipper, Janice Deng, Xue Yin, Logan R Ramjit, Zhenqing Ye, Yu Luan, H. Efsun Arda, Pei Wang
This study shows that Hippo pathway-mediated YAP1/TAZ inhibition is essential for pancreatic endocrine specification and differentiation, but not for beta-cell function.
eLife · Jun 17, 2024Peer-reviewedDevelopmental Biology