Author

Yi Xu

The University of Texas at San Antonio Health Science CenterORCID 0009-0007-4102-8797Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yi Xu9 papers · Chinese People's Liberation Army

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Pei WangiD· 3 shared Francis E. SharkeyiD· 2 shared Janice DengiD· 2 shared Jun LiuiD· 2 shared Kevin M LopeziD· 2 shared Michael H Nipper· 2 shared Yu LuaniD· 2 shared Angel A. Dominguez· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

Pei WangORCID

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3 papers

Recent·Most cited

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedJan 1, 2026

NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

Yi Xu, Michael H Nipper, Angel A. Dominguez…·Pei Wang

This study identifies NF2 as a critical tumor suppressor in PDAC, showing its role in promoting invasive behavior, enhancing cell fitness under stress, and contributing to drug resistance.

5 citationstop 1%

humanorganoid / primary culture

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Developmental BiologyeLifePeer-reviewedJun 17, 2024

Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation

Yifan Wu, Kunhua Qin, Yi Xu…·Pei Wang

This study shows that Hippo pathway-mediated YAP1/TAZ inhibition is essential for pancreatic endocrine specification and differentiation, but not for beta-cell function.

11 citations

mousestatistical model

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Molecular BiologyJournal of PancreatologyPeer-reviewedJan 16, 2024

Exploring the Role of YAP1 and TAZ in Pancreatic Acinar Cells and the Therapeutic Potential of VT-104 in Pancreatic Inflammation

Kevin M Lopez, Janice Deng, Yi Xu…·Jun Liu

This study investigates the role of YAP1 and TAZ in pancreatic inflammation and evaluates the therapeutic potential of VT-104 in a mouse model of pancreatitis.

2 citations

mouseexperimental assay

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