Author

Michael H Nipper

The University of Texas at San Antonio Health Science Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Pei WangiD· 2 shared Yi XuiD· 2 shared Yu LuaniD· 2 shared Angel A. Dominguez· 1 shared Chenhui He· 1 shared Daohong ZhouiD· 1 shared Francis E. SharkeyiD· 1 shared H. Efsun ArdaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Pei WangORCID

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2 papers

Recent·Most cited

NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

Yi Xu, Michael H Nipper, Angel A. Dominguez, Chenhui He, Francis E. Sharkey, Sajid Khan, Han Xu, Daohong Zhou, Lei Zheng, Yu Luan, Jun Liu, Pei Wang

This study identifies NF2 as a critical tumor suppressor in PDAC, showing its role in promoting invasive behavior, enhancing cell fitness under stress, and contributing to drug resistance.

Journal of Clinical Investigation · Jan 1, 2026Peer-reviewedCancer Biology

Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation

Yifan Wu, Kunhua Qin, Yi Xu, Shreya Rajhans, Truong Vo, Kevin M Lopez, Jun Liu, Michael H Nipper, Janice Deng, Xue Yin, Logan R Ramjit, Zhenqing Ye, Yu Luan, H. Efsun Arda, Pei Wang

This study shows that Hippo pathway-mediated YAP1/TAZ inhibition is essential for pancreatic endocrine specification and differentiation, but not for beta-cell function.

eLife · Jun 17, 2024Peer-reviewedDevelopmental Biology