Pei Wang

This study identifies NF2 as a critical tumor suppressor in PDAC, showing its role in promoting invasive behavior, enhancing cell fitness under stress, and contributing to drug resistance.

This study shows that Hippo pathway-mediated YAP1/TAZ inhibition is essential for pancreatic endocrine specification and differentiation, but not for beta-cell function.

This study investigates the role of YAP1 and TAZ in pancreatic inflammation and evaluates the therapeutic potential of VT-104 in a mouse model of pancreatitis.

This study shows that deleting Lats1 and Lats2 in adult mouse pancreatic acinar cells causes fibrosis and inflammation through YAP1/TAZ activation.