Author

Lorena Rocha

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Dorota Skowronska‐KrawczykiD· 3 shared Mary Jabari· 3 shared Viet Anh Nguyen HuuiD· 3 shared Claudia Palomino La Torre· 2 shared Michał KrawczykiD· 2 shared Qianlan XuiD· 2 shared Robert Neal WeinrebiD· 2 shared Alan SaghatelianiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMolecular Biology

Dorota Skowronska‐KrawczykORCID

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3 papers

Recent·Most cited

Accelerated aging induced by stress in experimental murine ocular hypertension.

Qianlan Xu, Cezary Rydz, Viet Anh Nguyen Huu, Lorena Rocha, Claudia Palomino La Torre, Irene Lee, William Cho, Mary Jabari, John E. Donello, Robert Neal Weinreb, David C. Lyon, Won‐Kyu Ju, Andrzej T. Foik, Dorota Skowronska‐Krawczyk

This study shows that repeated stress in young mice accelerates retinal aging at the transcriptional and epigenetic levels, highlighting the importance of early intervention for age-related eye diseases.

bioRxiv · May 1, 2022 · PreprintMolecular Biology

The Lipid Elongation Enzyme ELOVL2 is a molecular regulator of aging in the retina

Daniel Chen, Daniel L. Chao, Lorena Rocha, Matthew J. Kolar, Viet Anh Nguyen Huu, Michał Krawczyk, Manish Dasyani, Tina Wang, Maryam Jafari, Mary Jabari, Kevin D. Ross, Alan Saghatelian, Bruce A. Hamilton, Kang Zhang, Dorota Skowronska‐Krawczyk

This study shows that ELOVL2 regulates aging in the mouse retina by affecting fatty acid elongation and visual function, with potential therapeutic implications for age-related eye diseases.

Aging Cell · Jan 14, 2020Peer-reviewedMolecular Biology

Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension.

Lorena Rocha, Viet Anh Nguyen Huu, Claudia Palomino La Torre, Qianlan Xu, Mary Jabari, Michał Krawczyk, Robert Neal Weinreb, Dorota Skowronska‐Krawczyk

The paper shows that removing senescent cells early in a mouse model of ocular hypertension protects retinal ganglion cells from loss and preserves visual function.

Aging Cell · Dec 22, 2019Peer-reviewedMolecular Biology