Author

Irene Lee

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aaron D. VinyiD· 1 shared Andrzej T. FoikiD· 1 shared Arati K. SharmaiD· 1 shared Ava C. Knickerbocker· 1 shared B. Bishal PaudeliD· 1 shared Brian M. BarthiD· 1 shared Cezary RydziD· 1 shared Charlotte Rose Depew· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperSystems Biology

Aaron D. VinyORCID

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Author profile →

3 papers

Recent·Most cited

Effect of altered production and storage of dopamine on development and behavior in C. elegans

Irene Lee, Ava C. Knickerbocker, Charlotte Rose Depew, Elizabeth Martin, Jocelyn Dicent, Gary Wright Miller, Meghan L. Bucher

This study investigates how dopamine production and storage affect body size, development, and behavior in C. elegans, finding that increased dopamine production can rescue deficits caused by reduced dopamine sequestration.

Frontiers in Toxicology · Aug 16, 2024Peer-reviewedNeuroscience

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

B. Bishal Paudel, Su‐Fern Tan, Todd E. Fox, Johnson Ung, Upendarrao Golla, Jeremy J.P. Shaw, Wendy Dunton, Irene Lee, Wisam A. Fares, Satyam Patel, Arati K. Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles C. Cabot, , Thomas P. Loughran

This study identifies two sphingolipidomic subtypes in AML, with one subtype associated with poor clinical outcomes and high-risk features.

Blood Advances · Jan 3, 2024Peer-reviewedSystems Biology

Accelerated aging induced by stress in experimental murine ocular hypertension.

Qianlan Xu, Cezary Rydz, Viet Anh Nguyen Huu, Lorena Rocha, Claudia Palomino La Torre, Irene Lee, William Cho, Mary Jabari, John E. Donello, Robert Neal Weinreb, David C. Lyon, Won‐Kyu Ju, Andrzej T. Foik, Dorota Skowronska‐Krawczyk

This study shows that repeated stress in young mice accelerates retinal aging at the transcriptional and epigenetic levels, highlighting the importance of early intervention for age-related eye diseases.

bioRxiv · May 1, 2022 · PreprintMolecular Biology