Daniel Chen

Multilayer and Biomimetic Polycaprolactone/Uterine ECM Scaffold for Uterine Tissue Engineering and Anti-Adhesion Barrier Applications via 3D-Printing Near-Field Melt Electrowriting

This paper develops a 3D-printed multilayer scaffold combining polycaprolactone and decellularized uterine ECM hydrogel to create a biomimetic material for uterine tissue engineering and anti-adhesion barriers, showing improved mechanical and biological properties.

Distinctive cross-ancestry genetic architecture for age-related macular degeneration

This study identifies 63 AMD risk loci across multiple ancestries, highlighting ancestry-dependent genetic heterogeneity and potential therapeutic targets.

BAG3 regulation of Rab35 mediates the Endosomal Sorting Complexes Required for Transport /endolysosome pathway and tau clearance

This study identifies a BAG3-TBC1D10B-Rab35 regulatory axis that modulates ESCRT-dependent tau clearance and links its dysfunction to Alzheimer's disease pathogenesis.

The Lipid Elongation Enzyme ELOVL2 is a molecular regulator of aging in the retina

This study shows that ELOVL2 regulates aging in the mouse retina by affecting fatty acid elongation and visual function, with potential therapeutic implications for age-related eye diseases.