Author

Louise Andersson

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:simulation· 1

Frequent Co-Authors

Paweł KozielewicziD· 2 shared Adam K. SieradzaniD· 1 shared Alexander De Rosa· 1 shared David J. WalesiD· 1 shared Karine CheminiD· 1 shared Kittikorn WangriatisakiD· 1 shared Laura Jahrstorfer· 1 shared Maria P. GiliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Paweł KozielewiczORCID

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2 papers

Recent·Most cited

Decoding the Structural and Functional Impact of the Leukaemia-Associated A338V Mutation in GPR183

Louise Andersson, Patryk Adam Wesołowski, Laura Jahrstorfer, Alexander De Rosa, Tomas Heger, Vilmos Neuman, Adam K. Sieradzan, David J. Wales, Paweł Kozielewicz

This study examines how the A338V mutation in GPR183 affects receptor function, showing preserved G protein activation but impaired GRK2 and β-arrestin2 recruitment.

bioRxiv · Apr 1, 2026 · PreprintPharmacology & Toxicology

AI-Driven Virtual Screening and First-in-Class Conformational Biosensor Enable the Discovery of a GPR183 Inverse Agonist

Louise Andersson, Michele Roggia, Kittikorn Wangriatisak, Maria P. Gil, Karine Chemin, Sandro Cosconati, Paweł Kozielewicz

The paper discovers a GPR183 inverse agonist using AI-driven virtual screening and a conformational biosensor, showing inhibition of Gi activation and β-arrestin2 recruitment.

bioRxiv · Jun 19, 2025 · PreprintPharmacology & Toxicology