A chlorzoxazone-baclofen combination improves cerebellar impairment in spinocerebellar ataxia type 1
David D. Bushart, Haoran Huang, Luke J. Man, Logan M Morrison, Vikram G. Shakkottai
The paper identifies optimal chlorzoxazone-baclofen concentrations to improve cerebellar dysfunction in SCA1 without toxicity, proposing a dose escalation trial design.
Movement Disorders · Nov 5, 2020Peer-reviewedNeuroscience