Author

Logan M Morrison

University of MichiganORCID 0000-0002-7323-4137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Vikram G. ShakkottaiiD· 4 shared David D. BushartiD· 3 shared Haoran HuangiD· 3 shared Harry T. OrriD· 3 shared Hillary P. HandleriD· 2 shared Luke J. Man· 2 shared Billy Nguyen· 1 shared Chang‐Woo LeeiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

Vikram G. ShakkottaiORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Leon Tejwani, Neal G. Ravindra, Chang‐Woo Lee, Yubao Cheng, Billy Nguyen, Kimberly P. Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John T. Gionco, Yangfei Xiang, Jennifer Yoon, Hannah J. Ro, Fatema Haidery, Rosalie M. Grijalva, , Janghoo Lim

This study uses longitudinal single-nucleus RNA sequencing to analyze transcriptional dynamics in SCA1 cerebellum, identifying early cellular changes and applying deep learning to predict disease state.

Neuron · Nov 27, 2023Peer-reviewedNeuroscience

Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1

Logan M Morrison, Haoran Huang, Hillary P. Handler, Min Fu, David D. Bushart, Samuel S. Pappas, Harry T. Orr, Vikram G. Shakkottai

This study identifies increased intrinsic membrane excitability in SCA1-KI mice as a novel mechanism underlying hypertrophic olivary degeneration without inhibitory denervation.

bioRxiv · Oct 23, 2023 · PreprintNeuroscience

A chlorzoxazone-baclofen combination improves cerebellar impairment in spinocerebellar ataxia type 1

David D. Bushart, Haoran Huang, Luke J. Man, Logan M Morrison, Vikram G. Shakkottai

The paper identifies optimal chlorzoxazone-baclofen concentrations to improve cerebellar dysfunction in SCA1 without toxicity, proposing a dose escalation trial design.

Movement Disorders · Nov 5, 2020Peer-reviewedNeuroscience

Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1

Ravi Chopra, David D. Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang, Hillary P. Handler, Luke J. Man, Warunee Dansithong, Daniel R. Scoles, Stefan M. Pulst, Harry T. Orr, Vikram G. Shakkottai

Human Molecular Genetics · Sep 21, 2020Peer-reviewedNeuroscience