Author

Warunee Dansithong

University of Utah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Organism:rat· 2 Approach:statistical model· 2

Frequent Co-Authors

Daniel R. ScolesiD· 6 shared Stefan M. PulstiD· 6 shared Karla Patricia FigueroaiD· 5 shared Mandi GandelmaniD· 5 shared Sharan PauliD· 5 shared Collin J. AndersoniD· 3 shared David D. BushartiD· 1 shared Dhananjay YellajoshyulaiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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6 shared papersNeuroscience

Daniel R. ScolesORCID

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6 papers

Recent·Most cited

Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome

Collin J. Anderson, Karla Patricia Figueroa, Sharan Paul, Mandi Gandelman, Warunee Dansithong, Joseph A Katakowski, Daniel R. Scoles, Stefan M. Pulst

This study shows that viral vector-mediated SLC9A6 gene replacement improves cerebellar dysfunction and motor phenotypes in shaker rats with Christianson syndrome.

bioRxiv · Oct 31, 2024 · PreprintNeuroscience

Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat

Karla Patricia Figueroa, Collin J. Anderson, Sharan Paul, Warunee Dansithong, Mandi Gandelman, Daniel R. Scoles, Stefan M. Pulst

The paper identifies a Slc9a6 mutation causing Purkinje cell loss and ataxia in shaker rats and shows gene therapy can reverse the phenotype.

Human Molecular Genetics · Jan 9, 2023Peer-reviewedNeuroscience

Targeting Staufen 1 with antisense oligonucleotides for treating ALS and SCA2

Daniel R. Scoles, Sharan Paul, Warunee Dansithong, Karla Patricia Figueroa, Mandi Gandelman, Feliks Royzen, Collin J. Anderson, Stefan M. Pulst

This paper develops antisense oligonucleotides targeting STAU1 to treat ALS and SCA2, showing efficacy in reducing STAU1 expression and improving disease markers in mouse models.

bioRxiv · Nov 16, 2022 · PreprintNeuroscience

Staufen blocks autophagy in neurodegeneration

Sharan Paul, Warunee Dansithong, Mandi Gandelman, Karla Patricia Figueroa, Tao Zu, Laura P.W. Ranum, Daniel R. Scoles, Stefan M. Pulst

The paper investigates how STAU1 interacts with mTOR to hyperactivate it and inhibit autophagy in neurodegenerative disease models.

bioRxiv · Mar 30, 2022 · PreprintNeuroscience

Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1

Ravi Chopra, David D. Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang, Hillary P. Handler, Luke J. Man, Warunee Dansithong, Daniel R. Scoles, Stefan M. Pulst, Harry T. Orr, Vikram G. Shakkottai

Human Molecular Genetics · Sep 21, 2020Peer-reviewedNeuroscience

Staufen 1 amplifies pro-apoptotic activation of the unfolded protein response.

Mandi Gandelman, Warunee Dansithong, Karla Patricia Figueroa, Sharan Paul, Daniel R. Scoles, Stefan M. Pulst

This study identifies STAU1 as a modulator of the UPR that promotes apoptosis via the PERK-CHOP pathway in response to ER stress.

Cell Death and Differentiation · May 15, 2020Peer-reviewedNeuroscience