Luke P. Lee

Chirality-Driven Photonic PCR Enables Label-Free Genetic Amplification

This paper introduces a chirality-driven photonic PCR method that enables rapid, label-free genetic amplification by using chiral plasmonic nanoparticles to enhance photothermal conversion and DNA synthesis efficiency.

Cascaded Nano-ring Dialyzer for Continuous Regenerative Peritoneal Dialysis

This paper develops a continuous regenerative peritoneal dialysis system using cascaded nano-ring dialyzers, achieving toxin removal in a canine model.

Cryptic disease-prone states in human mesocortical assembloids revealed by multimodal profiling

The paper identifies disease-prone states in human mesocortical assembloids using multimodal profiling, revealing intrinsic susceptibility to neurodegeneration.

EVscope: A Comprehensive Bioinformatics Pipeline for Accurate and Robust Analysis of Total RNA Sequencing from Extracellular Vesicles

EVscope is a bioinformatics pipeline for analyzing EV RNA-seq data, improving read assignment and contamination correction with a comprehensive annotation and visualization tool.

Human Stem Cell-derived Kidney Collecting Duct Model via Epithelial Microphysiological Analysis Platform: Epi-MAP

This paper introduces a human kidney epithelial microphysiological platform (Epi-MAP) to model collecting duct physiology from stem cells, enabling advanced functional analysis and drug testing.

Dynamic Kidney Organoid Microphysiological Analysis Platform

This paper introduces a dynamic kidney organoid microphysiological analysis platform to improve reproducibility, accuracy, and utility in kidney research and drug development.

Brainwaves Monitoring via Human Midbrain Organoids Microphysiological Analysis Platform: MAP

This paper introduces a microphysiological platform for long-term monitoring of midbrain organoids, capturing electrophysiological development and modeling Parkinson's disease-like alterations.

Unveiling the Secrets of Extracellular Vesicles in Urban Water Systems: Understanding the Link Between Human and Environmental Health

This study investigates extracellular vesicles in urban water systems to link human activities with microbial community impacts on public health and river biodiversity.