Author

Luke Zhao

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Aaron D. GitleriD· 2 shared Gregg A. DuncaniD· 2 shared Juliane Bombosch· 2 shared Olivia GautieriD· 2 shared Taj YeruvaiD· 2 shared Yi ZengiD· 2 shared Andrew LookaiD· 1 shared Arwa Kathira· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Aaron D. GitlerORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Sprayable in Situ Forming PEG Hydrogels for Intranasal Drug Delivery

Luke Zhao, Gregg A. Duncan, Taj Yeruva

This paper develops a PEG-based hydrogel for intranasal drug delivery that forms in situ without physiological triggers, improving drug residence time and bioavailability.

bioRxiv · Sep 18, 2026 · PreprintBioengineering

KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS

Tetsuya Akiyama, Yi Zeng, Caiwei Guo, Olivia Gautier, Lauren S. Koepke, Heankel Lyons, Elana Molotsky, Juliane Bombosch, Odilia Sianto, Jay P. Ross, Phuong T. Hoang, Luke Zhao, Cole Spencer, Charlotte J. Sumner, Michelle Monje, , Aaron D. Gitler

This study shows that SMN deficiency reduces KIF5A in SMA, impairing axon regeneration, and links SMA and ALS through KIF5A stabilization by SMN.

JCI Insight · Mar 26, 2026Peer-reviewedNeuroscience

An emergent disease-associated motor neuron state precedes cell death in a mouse model of ALS

Olivia Gautier, Jacob A. Blum, Thao P. Nguyen, Sandy L. Klemm, Mai Yamakawa, Nasa Sinnott-Armstrong, Yi Zeng, Chung-ha O. Davis, Juliane Bombosch, Lisa Nakayama, Kevin A. Guttenplan, Derek C. Chen, Arwa Kathira, Luke Zhao, Jessica E. Rexach, , Aaron D. Gitler

The paper identifies a disease-associated motor neuron state in a mouse ALS model that precedes cell death and links it to human ALS genetic risk factors.

bioRxiv · Aug 21, 2025 · PreprintNeuroscience

Rapid in situ forming PEG hydrogels for mucosal drug delivery

Taj Yeruva, Robert J. Morris III, Sahana Kumar, Luke Zhao, Peter Kofinas, Gregg A. Duncan

This paper develops rapid in situ forming PEG hydrogels for mucosal drug delivery that degrade naturally and adhere to mucus-coated tissues.

Biomaterials Science · Jan 1, 2025Peer-reviewedBioengineering

Metabolic demand regulates selective cell death in Parkinson's Disease

Luke Zhao, Ishaan Nanal, Linxi Wang, Andrew Looka, Marianne J. Bezaire

This study investigates how metabolic demand influences selective cell death in Parkinson's Disease by simulating neural cells with altered biophysical properties.

bioRxiv · Oct 24, 2021 · PreprintNeuroscience