Kevin A. Guttenplan

The paper identifies a disease-associated motor neuron state in a mouse ALS model that precedes cell death and links it to human ALS genetic risk factors.

This study identifies adrenergic signaling as a gatekeeper for astrocyte responses to neurotransmitters, showing its role in regulating neuronal activity and behavior in both Drosophila and mammals.

This study develops a fluorescent Aβ analogue to monitor glial cell phagocytosis of amyloid β in real time, showing microglia uptake exceeds astrocytes.

This study profiles single-nucleus transcriptomes of adult mouse spinal motor neurons to identify transcriptional subtypes and their functional roles.