M. C. Maiden

Genomic library of Bordetella

The paper creates a unified genomic library of Bordetella strains, revealing new species and phylogenetic insights, and provides resources for studying Bordetella evolution and epidemiology.

Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter

The paper quantifies horizontal gene transfer (HGT) between Campylobacter species with different host ecologies, showing cohabitation in the same host increases HGT by 6-fold.

A two-hit epistasis model prevents core genome disharmony in recombining bacteria

The paper shows that recombination in bacteria can overcome genomic disharmony through a two-hit epistasis model, allowing beneficial gene combinations to be reinstated in new genetic backgrounds.

Deep sequencing reveals Campylobacter in commercial meat chickens less than 8 days old.

The paper uses molecular methods to detect Campylobacter in young chickens, finding that most carry the bacteria before traditional culture methods can detect it.

A mathematical modelling approach to uncover factors influencing the spread of Campylobacter in a flock of chickens

The paper uses Bayesian models to analyze Campylobacter spread in chickens, finding that seasonal variation and bird health influence prevalence of different species.

Targeted metagenomic sequencing enhances the identification of pathogens associated with acute infection.

Castanet, a targeted metagenomic sequencing method, improves pathogen detection in clinical samples by combining sensitivity with cost-effectiveness and broad organism coverage.

Domestication of Campylobacter jejuni NCTC 11168

This study compares genetic and phenotypic variation in 23 isolates of the reference Campylobacter jejuni strain NCTC 11168, showing significant genomic and phenotypic differences despite being considered identical.