Author

K. L. Christman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:rat· 4 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

C. Luo· 2 shared M. Alperin· 2 shared M. Dzieciatkowska· 2 shared A. M. Vahabzadeh-Hagh· 1 shared A. N. DeMaria· 1 shared A. Panduro· 1 shared B. Q. Pham· 1 shared B. Shergill· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. Luo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction

Y. Liang, H. Sullivan, K. Carrow, J. Korpanty, K. Worthington, C. Luo, K. L. Christman, N. C. Gianneschi

This paper develops biodegradable micellar nanoparticles responsive to inflammation, showing targeted accumulation in myocardial infarction sites in rats.

Journal of the American Chemical Society · May 15, 2023Peer-reviewedBiochemistry

Immunomodulatory Extracellular Matrix Hydrogel Mitigates Scar Formation in a Model of Tongue Fibrosis.

E. I. Zelus, A. Panduro, M. Alperin, A. M. Vahabzadeh-Hagh, K. L. Christman

This study uses a decellularized extracellular matrix hydrogel to reduce scar formation and improve muscle regeneration in a rat model of tongue fibrosis.

bioRxiv · May 17, 2022 · PreprintBioengineering

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction

R. H. F. Bender, B. T. O'Donnell, B. Shergill, B. Q. Pham, D. J. Juat, M. S. Hatch, V. S. Shirure, M. Wortham, K.-V. Nguyen-Ngoc, Y. Jun, R. Gaetani, K. L. Christman, L. Teyton, S. C. George, M. Sander, C. C. Hughes

This paper develops a vascularized 3D model of human pancreatic islets to study immune cell interactions and islet destruction in diabetes.

bioRxiv · Dec 21, 2021Cell Biology

Pro-regenerative Extracellular Matrix Hydrogel Prevents and Mitigates Pathological Alterations of Pelvic Muscles Following Birth Injury

P. Duran, F. B. Sesillo, L. Burnett, S. A. Menefee, M. Cook, G. Zazueta-Damian, M. Dzieciatkowska, E. Do, S. French, M. M. Shah, C. Sanvictores, K. Hansen, M. Shtrahman, K. L. Christman, M. Alperin

This study shows that an extracellular matrix hydrogel prevents and reduces muscle atrophy and fibrosis in pelvic floor muscles after birth injury in rats.

bioRxiv · May 28, 2021 · PreprintBioengineering

Tissue specific muscle extracellular matrix hydrogel improves skeletal muscle regeneration in vivo over non-matched tissue source

J. L. Ungerleider, M. Dzieciatkowska, K. C. Hansen, K. L. Christman

This study shows that tissue-specific muscle ECM hydrogels enhance skeletal muscle regeneration in mice compared to non-matched tissue sources and saline.

bioRxiv · Jun 30, 2020 · PreprintBioengineering

Healing Tissues From the Inside Out: Infusible Biomaterial for Targeting and Treating Inflammatory Tissues via Intravascular Administration

M. T. Spang, T. S. Lazerson, S. Bhatia, J. Corbitt, G. Sandoval, C. Luo, K. G. Osborn, P. Cabrales, E. Kwon, F. Contijoch, R. R. Reeves, A. N. DeMaria, K. L. Christman

This study develops a new ECM therapy for intravascular infusion to target and treat inflammatory tissues, showing improved tissue repair and reduced inflammation in animal models of MI and other injuries.

bioRxiv · Apr 10, 2020 · PreprintBioengineering