Author

M. B. Goodman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Biophysics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 3 Assay:behavioral assay· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

B. L. Pruitt· 3 shared L. Wang· 2 shared A. Das· 1 shared A. L. Nekimken· 1 shared A. Sanzeni· 1 shared B. Huynh· 1 shared B. Mulcahy· 1 shared B. Petzold· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCell Biology

B. L. Pruitt

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Author profile →

4 papers

Recent·Most cited

Conserved basal lamina proteins, laminin and nidogen, are repurposed to organize mechanosensory complexes responsible for touch sensation.

A. Das, J. A. Franco, B. Mulcahy, L. Wang, D. Chapman, C. Jaisinghani, B. L. Pruitt, M. Zhen, M. B. Goodman

This study shows that laminin and nidogen in the basal lamina form complexes with the MEC-4 channel to enable touch sensation in C. elegans.

bioRxiv · Feb 11, 2022 · PreprintCell Biology

DEG/ENaC/ASIC channels vary in their sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs

S. Fechner, I. D'Alessandro, L. Wang, C. Tower, L. Tao, M. B. Goodman

The paper examines drug sensitivity variations among C. elegans DEG/ENaC/ASIC channels, showing some are insensitive to amiloride and NSAIDs can inhibit or potentiate them.

Journal of General Physiology · Mar 3, 2021Peer-reviewedBiophysics

Tissue mechanics and somatosensory neural responses govern touch sensation in C. elegans

A. Sanzeni, S. Katta, B. Petzold, B. L. Pruitt, M. B. Goodman, M. Vergassola

This study develops a quantitative model to explain touch sensation in C. elegans by integrating tissue mechanics and neural responses to indentation stimuli.

bioRxiv · Nov 16, 2018 · PreprintNeuroscience

The Tactile Receptive Fields of Freely Moving Caenorhabditis elegans Nematodes

E. A. Mazzochette, A. L. Nekimken, F. Loizeau, J. Whitworth, B. Huynh, M. B. Goodman, B. L. Pruitt

This paper develops an automated system to study touch responses in C. elegans and finds two distinct tactile receptive fields on the worm's body surface.

bioRxiv · Mar 5, 2018Animal Behavior & Cognition