Author

M. Zhen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Mulcahy· 2 shared A. Bigot· 1 shared A. Das· 1 shared B. A. Stewart· 1 shared B. L. Pruitt· 1 shared C. Jaisinghani· 1 shared C. T. Nguyen· 1 shared C. Yi· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

B. Mulcahy

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Author profile →

4 papers

Recent·Most cited

Isolation of a Chlamydia Strain from Lung Tissue Samples in Healthy Chickens Exhibiting Antagonistic Effects on Avian Infectious Bronchitis Virus

M. Zhen

The paper isolates Chlamydia strains from healthy chickens that inhibit avian infectious bronchitis virus, showing antiviral activity and cell-autonomous effects.

bioRxiv · May 10, 2023 · PreprintMicrobiology

Conserved basal lamina proteins, laminin and nidogen, are repurposed to organize mechanosensory complexes responsible for touch sensation.

A. Das, J. A. Franco, B. Mulcahy, L. Wang, D. Chapman, C. Jaisinghani, B. L. Pruitt, M. Zhen, M. B. Goodman

This study shows that laminin and nidogen in the basal lamina form complexes with the MEC-4 channel to enable touch sensation in C. elegans.

bioRxiv · Feb 11, 2022 · PreprintCell Biology

View-channel-depth light-field microscopy: real-time volumetric reconstruction of biological dynamics by deep learning

Z. Wang, L. Zhu, H. Zhang, G. Li, Y. Li, Y. Yang, Y. Ding, S. Gao, T. K. Hsiai, P. Fei, M. Zhen, C. Yi

This paper introduces a deep learning method to improve light-field microscopy, enabling high-speed, artifact-free volumetric imaging of biological processes.

Nature Methods · Feb 11, 2021Peer-reviewedBiophysics

A three-dimensional culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction and disease modeling

M. Afshar Bakooshli, E. S. Lippmann, B. Mulcahy, N. Iyer, C. T. Nguyen, K. Tung, B. A. Stewart, H. van den Dorpel, T. Fuehrmann, M. S. Shoichet, A. Bigot, E. Pegoraro, H. Ahn, H. Ginsberg, M. Zhen, , P. M. Gilbert

This paper introduces a 3D co-culture model of human skeletal muscle and motor neurons to study adult neuromuscular junction development and disease, showing increased receptor upregulation and disease modeling capability.

bioRxiv · Nov 26, 2018 · PreprintBioengineering