Conserved basal lamina proteins, laminin and nidogen, are repurposed to organize mechanosensory complexes responsible for touch sensation.
A. Das, J. A. Franco, B. Mulcahy, L. Wang, D. Chapman, C. Jaisinghani, B. L. Pruitt, M. Zhen, M. B. Goodman
This study shows that laminin and nidogen in the basal lamina form complexes with the MEC-4 channel to enable touch sensation in C. elegans.
bioRxiv · Feb 11, 2022 · PreprintCell Biology