Author

M. Ballif

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1

Frequent Co-Authors

S. Gagneux· 3 shared A. Avihingsanon· 2 shared C. Loiseau· 2 shared D. Brites· 2 shared L. Fenner· 2 shared L. K. Rutaihwa· 2 shared M. Egger· 2 shared M. Reinhard· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersEvolutionary Biology

S. Gagneux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HIV coinfection is associated with low fitness rpoB variants in rifampicin-resistant Mycobacterium tuberculosis

C. Loiseau, D. Brites, M. Reinhard, K. Zuercher, S. Borrell, M. Ballif, L. Fenner, H. Cox, L. K. Rutaihwa, R. J. Wilkinson, M. Yotebieng, E. J. Carter, A. Abimiku, O. Marcy, E. Gotuzzo, , S. Gagneux

The paper analyzes drug-resistant Mtb genomes from HIV coinfected and HIV negative patients, finding that HIV coinfected patients have more low fitness rpoB variants in rifampicin-resistant strains.

bioRxiv · Jul 20, 2020Evolutionary Biology

Multiple Introductions of the Mycobacterium tuberculosis Lineage 2 Beijing into Africa over centuries

L. K. Rutaihwa, F. Menardo, D. Stucki, S. M. Gygli, S. D. Ley, B. Malla, J. Feldmann, S. Borrell Farnov, C. Beisel, K. Middelkoop, J. E. Carter, L. Diero, M. Ballif, L. Jugheli, K. Reither, , S. Gagneux

This study uses whole genome sequences to show that L2-Beijing tuberculosis strains were introduced multiple times into Africa from East and Southeast Asia over the past 300 years, likely due to hypervirulence and transmissibility.

bioRxiv · Sep 10, 2018Evolutionary Biology

Whole genome sequencing for drug resistance profile prediction in Mycobacterium tuberculosis

S. M. Gygli, P. M. Keller, M. Ballif, N. Blöchliger, R. Hömke, M. Reinhard, C. Loiseau, C. Ritter, P. Sander, S. Borrell, J. C. Loo, A. Avihingsanon, J. Gnokoro, M. Yotebieng, M. Egger, , E. C. Böttger

This study uses whole genome sequencing to predict drug resistance profiles in M. tuberculosis isolates, achieving high sensitivity and specificity compared to phenotypic testing.

bioRxiv · Aug 28, 2018Microbiology