Author

M. Reinhard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Loiseau· 4 shared S. Borrell· 4 shared S. Gagneux· 4 shared A. Avihingsanon· 2 shared A. Trauner· 2 shared D. Brites· 2 shared J. Feldmann· 2 shared M. Ballif· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

C. Loiseau

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HIV coinfection is associated with low fitness rpoB variants in rifampicin-resistant Mycobacterium tuberculosis

C. Loiseau, D. Brites, M. Reinhard, K. Zuercher, S. Borrell, M. Ballif, L. Fenner, H. Cox, L. K. Rutaihwa, R. J. Wilkinson, M. Yotebieng, E. J. Carter, A. Abimiku, O. Marcy, E. Gotuzzo, , S. Gagneux

The paper analyzes drug-resistant Mtb genomes from HIV coinfected and HIV negative patients, finding that HIV coinfected patients have more low fitness rpoB variants in rifampicin-resistant strains.

bioRxiv · Jul 20, 2020Evolutionary Biology

The Evolution of Fluoroquinolone-Resistance in Mycobacterium tuberculosis is Modulated by the Genetic Background

R. A. D. Castro, A. Ross, L. Kamwela, M. Reinhard, C. Loiseau, J. Feldmann, S. Borrell, A. Trauner, S. Gagneux

This study shows that the genetic background of Mycobacterium tuberculosis significantly affects the evolution of fluoroquinolone resistance in both in vitro experiments and clinical isolates.

bioRxiv · Jun 3, 2019Microbiology

Whole genome sequencing for drug resistance profile prediction in Mycobacterium tuberculosis

S. M. Gygli, P. M. Keller, M. Ballif, N. Blöchliger, R. Hömke, M. Reinhard, C. Loiseau, C. Ritter, P. Sander, S. Borrell, J. C. Loo, A. Avihingsanon, J. Gnokoro, M. Yotebieng, M. Egger, , E. C. Böttger

This study uses whole genome sequencing to predict drug resistance profiles in M. tuberculosis isolates, achieving high sensitivity and specificity compared to phenotypic testing.

bioRxiv · Aug 28, 2018Microbiology

Reference Set of Mycobacterium tuberculosis Clinical Strains: A tool for research and product development

S. Borrell, A. Trauner, D. Brites, L. Rigouts, C. Loiseau, M. Coscolla, S. Niemann, B. De Jong, D. Yeboah-Manu, M. Kato-Maeda, J. Feldmann, M. Reinhard, C. Beisel, S. Gagneux

The paper introduces a reference set of 20 genetically characterized Mycobacterium tuberculosis clinical strains to enhance TB research by incorporating phylogenetic diversity beyond the commonly used lab strains.

bioRxiv · Aug 25, 2018Microbiology