M. Bassik

SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter

This study identifies SLC12A9 as a lysosomal ammonium exporter that maintains lysosomal homeostasis by transporting ammonium and chloride.

Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages

This study uses CRISPR screening to identify C3aR as critical for macrophage capture of fungi, revealing a novel role in fungal pathogen recognition.