Tissue protective role of Ganetespib in SARS-CoV-2-infected Syrian golden hamsters
L. G. Teixeira Alves, M. Baumgardt, J. Hoppe, T. C. Firsching, J. M. Adler, G. Mastrobuoni, J. Grobe, K. Hoenzke, S. Kempa, A. D. Gruber, A. C. Hocke, J. Trimpert, E. Wyler, M. Landthaler
This study shows that Ganetespib, an HSP90 inhibitor, reduces SARS-CoV-2 replication and inflammation in vitro and improves clinical outcomes in infected Syrian golden hamsters.
bioRxiv · Dec 27, 2022 · PreprintMicrobiology