A Cell-Permeable Nanobody to Restore F508del Cystic Fibrosis Transmembrane Conductance Regulator Activity
L. Franz, T. Rubil, A. Balazs, M. Overtus, K. Kemnitz-Hassanin, C. Govaerts, M. A. Mall, C. P. Hackenberger
This paper develops a cell-permeable nanobody to restore function of the misfolded F508del-CFTR protein in CF bronchial epithelial cells.
bioRxiv · Apr 26, 2024Biochemistry