Author

M. Bechtel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Bojkova· 6 shared M. Michaelis· 6 shared S. Ciesek· 6 shared M. N. Wass· 5 shared J. Cinatl· 4 shared T. Rothenburger· 3 shared J. D. Kandler· 2 shared J. Kandler· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersMicrobiology

D. Bojkova

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Repurposing of the antibiotic nitroxoline for the treatment of mpox

D. Bojkova, N. Zoeller, M. Tietgen, K. Steinhorst, M. Bechtel, T. Rothenburger, J. D. Kandler, J. Schneider, V. M. Corman, S. Ciesek, H. F. Rabenau, M. N. Wass, S. Kippenberger, S. Göttig, M. Michaelis, J. Cinatl

This study shows nitroxoline, an antibiotic, inhibits mpox virus replication and remains effective against tecovirimat-resistant strains, suggesting it as a repurposing candidate for mpox treatment.

bioRxiv · Dec 29, 2022Microbiology

Omicron-induced interferon signalling prevents influenza A virus infection

D. Bojkova, M. Bechtel, T. Rothenburger, J. D. Kandler, L. Hayes, R. Olmer, U. Martin, D. Jonigk, S. Ciesek, M. N. Wass, M. Michaelis, J. Cinatl

This study shows Omicron variants induce interferon responses in human cells, protecting against influenza A virus super-infection, while Delta does not.

bioRxiv · Sep 6, 2022 · PreprintMicrobiology

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform

D. Bojkova, P. Reus, L. Panosch, M. Bechtel, T. Rothenburger, J. Kandler, A. Pfeiffer, J. U. Wagner, M. Shumliakivska, S. Dimmeler, R. Olmer, U. Martin, F. Vondran, T. Toptan, F. Rothweiler, , J. Cinatl

This study develops a phenotypic screening platform using caspase 3/7 activity to identify antiviral compounds against SARS-CoV-2, including novel candidates and combinations.

bioRxiv · Jul 17, 2022Pharmacology & Toxicology

CD47 as a potential biomarker for the early diagnosis of severe COVID-19

K.-M. McLaughlin, D. Bojkova, M. Bechtel, J. Kandler, P. Reus, T. Le, J. U. Wagner, S. Ciesek, M. N. Wass, M. Michaelis, J. N. Cinatl

This study identifies CD47 as a potential biomarker for early diagnosis of severe COVID-19 by showing its increased levels in SARS-CoV-2 infection and association with risk factors and complications.

bioRxiv · Mar 1, 2021 · PreprintMicrobiology

Targeting pentose phosphate pathway for SARS-CoV-2 therapy

D. Bojkova, R. Costa, M. Bechtel, S. Ciesek, M. Michaelis, J. Cinatl

This study identifies the pentose phosphate pathway as a target for SARS-CoV-2 therapy and shows that inhibiting it with benfooxythiamine reduces viral replication.

bioRxiv · Aug 19, 2020Microbiology

COVID-19-related coagulopathy, is transferrin a missing link?

K.-M. McLaughlin, M. Bechtel, D. Bojkova, S. Ciesek, M. N. Wass, M. Michaelis, J. N. Cinatl

The paper identifies transferrin as a potential coagulation promoter in COVID-19, showing age-related increases, sex differences, and upregulation upon infection.

Diagnostics · Jul 30, 2020Peer-reviewedMicrobiology