Author

M. C. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Bezault· 1 shared B. Rodriguez de Francisco· 1 shared B. Wang· 1 shared B. Wong Jern Han· 1 shared C. Sauvanet· 1 shared C. Y. Tham· 1 shared D. Babu· 1 shared D. Hanein· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Bezault

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tract

C. Sauvanet, M. Lemos, A. Bezault, B. Rodriguez de Francisco, M. C. Chan, K. P. Hui, K.-c. Ng, J. M. Nicholls, N. Volkmann, D. Hanein

This study develops hACE2 nanoparticles that block SARS-CoV-2 and its variants by sequestering viruses through aggregation in cell systems and human respiratory tract explants.

bioRxiv · May 5, 2022 · PreprintCell Biology

Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia

B. Wang, L. Kong, D. Babu, R. Choudhary, W. Fam, J. Q. Tng, Y. Goh, B. Wong Jern Han, X. Liu, F. F. Song, P. Chia, M. C. Chan, O. An, C. Y. Tham, T. Benoukraf, , M. J. Fullwood

This study maps 3D genome organization in normal and AML haematopoietic stem cells, finding increased chromatin loops to oncogenes in AML and identifying MEIS1 and HOXA9 as key oncogenes regulated by these interactions.

bioRxiv · Apr 18, 2020 · PreprintCancer Biology