Author

C. Y. Tham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Bertoletti· 2 shared A. Chia· 2 shared A. T. Tan· 2 shared J. G. Low· 2 shared K. Kunasegaran· 2 shared L.-F. Wang· 2 shared N. Le Bert· 2 shared S. Kalimuddin· 2 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Bertoletti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection

N. Le Bert, H. E. Clapham, A. T. Tan, W. N. Chia, C. Y. Tham, J. M. Lim, K. Kunasegaran, L. Tan, C.-A. Dutertre, N. Shankar, J. M. Lim, L. J. Sun, M. Zahari, Z. M. Tun, V. Kumar, , C. C. Tam

This study compares T cell responses in asymptomatic and symptomatic SARS-CoV-2感染者, finding that asymptomatic individuals have a robust and functional immune response with balanced cytokine production.

bioRxiv · Nov 25, 2020Immunology

Early induction of SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

A. T. Tan, M. Linster, C. Tan, N. Le Bert, W. Chia, K. Kunasegaran, Y. Zhuang, C. Y. Tham, A. Chia, G. J. Smith, B. E. Young, S. Kalimuddin, J. G. Low, D. Lye, L.-F. Wang, A. Bertoletti

The paper examines the relationship between SARS-CoV-2 specific T cell responses and disease severity in COVID-19 patients, finding that early T cell induction correlates with mild disease and faster viral clearance.

bioRxiv · Oct 15, 2020Immunology

Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia

B. Wang, L. Kong, D. Babu, R. Choudhary, W. Fam, J. Q. Tng, Y. Goh, B. Wong Jern Han, X. Liu, F. F. Song, P. Chia, M. C. Chan, O. An, C. Y. Tham, T. Benoukraf, , M. J. Fullwood

This study maps 3D genome organization in normal and AML haematopoietic stem cells, finding increased chromatin loops to oncogenes in AML and identifying MEIS1 and HOXA9 as key oncogenes regulated by these interactions.

bioRxiv · Apr 18, 2020 · PreprintCancer Biology