Author

M. C. Kasperek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. M. Allen· 2 shared M. E. Caetano-Silva· 2 shared A. F. Duff· 1 shared A. Shrestha· 1 shared A. V. Ulanov· 1 shared A. Velasquez Galeas· 1 shared C. H. Lin· 1 shared D. A. Wainwright· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

J. M. Allen

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2 papers

Recent·Most cited

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation

M. E. Caetano-Silva, A. Shrestha, A. F. Duff, D. Kontic, P. C. Brewster, M. C. Kasperek, C. H. Lin, D. A. Wainwright, D. H. Saavedra, J. A. Woods, M. T. Bailey, T. W. Buford, J. M. Allen

This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.

bioRxiv · Mar 22, 2024Immunology

Microbial aromatic amino acid metabolism is modifiable in fermented food matrices to promote bioactivity

M. C. Kasperek, A. Velasquez Galeas, M. E. Caetano-Silva, Z. Xie, A. V. Ulanov, M. R. La Frano, S. Devkota, M. J. Miller, J. M. Allen

This study identifies aryl-lactates as bioactive metabolites in fermented foods and shows their production can be enhanced to boost AhR receptor activity.

bioRxiv · Dec 21, 2023Microbiology