Author

D. A. Wainwright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. F. Duff· 1 shared A. Khan· 1 shared A. M. Armando· 1 shared A. Rzhetsky· 1 shared A. Shrestha· 1 shared B. F. Cravatt· 1 shared B. Prager· 1 shared C. H. Lin· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. F. Duff

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Author profile →

2 papers

Recent·Most cited

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation

M. E. Caetano-Silva, A. Shrestha, A. F. Duff, D. Kontic, P. C. Brewster, M. C. Kasperek, C. H. Lin, D. A. Wainwright, D. H. Saavedra, J. A. Woods, M. T. Bailey, T. W. Buford, J. M. Allen

This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.

bioRxiv · Mar 22, 2024Immunology

Targeting Glioblastoma Signaling and Metabolism with A Re-Purposed Brain-Penetrant Drug

J. Bi, A. Khan, J. Tang, S. Wu, W. Zhang, R. C. Gimple, T. Koga, A. M. Armando, S. Miki, H. Yang, B. Prager, E. J. Curtis, D. A. Wainwright, F. B. Furnari, J. N. Rich, , P. S. Mischel

This study identifies fluoxetine as a potential therapy for glioblastoma by inhibiting SMPD1 and enhancing temozolomide efficacy, with real-world evidence suggesting improved survival.

bioRxiv · Mar 16, 2021Cancer Biology