Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation
M. E. Caetano-Silva, A. Shrestha, A. F. Duff, D. Kontic, P. C. Brewster, M. C. Kasperek, C. H. Lin, D. A. Wainwright, D. H. Saavedra, J. A. Woods, M. T. Bailey, T. W. Buford, J. M. Allen
This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.
bioRxiv · Mar 22, 2024Immunology