The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
E. Fernandez Garcia, U. Paudel, M. C. Noji, C. E. Bowman, J. R. Pitarresi, A. K. Rustgi, K. E. Wellen, Z. Arany, J. S. Weissenrieder, J. K. Foskett
This study shows that the mitochondrial Ca2+ channel MCU supports tumor growth by enabling cell cycle progression and proliferation through mitochondrial Ca2+ uptake, despite unchanged mitochondrial function.
bioRxiv · Apr 26, 2023 · PreprintCancer Biology