Author

J. K. Foskett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

R. Payne· 2 shared A. K. Rustgi· 1 shared A. Trautz· 1 shared C. A. Natale· 1 shared C. Aguirre-Portoles· 1 shared C. E. Bowman· 1 shared C. Li· 1 shared E. Fernandez Garcia· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

R. Payne

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation

E. Fernandez Garcia, U. Paudel, M. C. Noji, C. E. Bowman, J. R. Pitarresi, A. K. Rustgi, K. E. Wellen, Z. Arany, J. S. Weissenrieder, J. K. Foskett

This study shows that the mitochondrial Ca2+ channel MCU supports tumor growth by enabling cell cycle progression and proliferation through mitochondrial Ca2+ uptake, despite unchanged mitochondrial function.

bioRxiv · Apr 26, 2023 · PreprintCancer Biology

Strongly coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca2+ uptake

H. Vais, R. Payne, C. Li, J. K. Foskett

This study identifies a regulatory mechanism where coupled Ca2+-regulatory mechanisms on both sides of the mitochondrial inner membrane control MCU-mediated Ca2+ uptake.

bioRxiv · Apr 7, 2020Biophysics

ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

C. Aguirre-Portoles, R. Payne, A. Trautz, J. K. Foskett, C. A. Natale, J. T. Seykora, T. W. Ridky

The paper identifies ZIP9 as a target of testosterone in melanoma and shows that androgen receptor inhibitors can block ZIP9 to suppress melanoma growth in males.

bioRxiv · Mar 12, 2020Cancer Biology