Author

M. C. Tal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

I. L. Weissman· 3 shared E. Gars· 2 shared FinnGen· 2 shared H. Ollila· 2 shared M. Shoham· 2 shared P. Hansen· 2 shared Q. Feng· 2 shared T. Raveh· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersImmunology

I. L. Weissman

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3 papers

Recent·Most cited

P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi

M. C. Tal, P. S. Hansen, H. A. Ogasawara, Q. Feng, R. F. Volk, B. Lee, S. E. Casebeer, G. S. Blacker, M. Shoham, S. D. Galloway, A. L. Sapiro, L.-B. T. Dulgeroff, T. Raveh, V. R. Pothineni, H.-H. S. Potula, , B. W. Zaro

This study identifies P66, a bacterial protein mimicking CD47, which binds SIRPα to evade macrophage phagocytosis, and shows its role in Lyme Disease pathogenesis.

bioRxiv · Apr 29, 2024 · PreprintImmunology

SIRPα controls CD47-dependent platelet clearance in mice and humans

M. Shoham, Y. Y. Yiu, P. Hansen, A. Subramaniam, M. Broberg, E. Gars, T. Raveh, FinnGen, I. L. Weissman, N. Sinnott-Armstrong, A. Krishnan, H. Ollila, M. C. Tal

This study shows that the CD47-SIRP axis regulates platelet homeostasis and that blocking this interaction affects platelet levels in mice and humans.

bioRxiv · Dec 9, 2023 · PreprintImmunology

Novel Association of Lyme Disease, Age, and Atopic Dermatitis

B. T. Lee, S. Galloway, Q. Feng, S. Strausz, P. Hansen, L. B. Torrez-Dulgeroff, G. Blacker, Y. Y. Yiu, P. Mansfield, FinnGen, A. Saleem, E. Gars, E. Sanders, I. L. Weissman, H. Ollila, M. C. Tal

This study identifies a novel association between Lyme disease, age, and atopic dermatitis using both murine models and human epidemiological data.

bioRxiv · Jan 27, 2022 · PreprintImmunology