Author

M. Caza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:fungi (other)· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Hu· 4 shared J. W. Kronstad· 4 shared R. Attarian· 2 shared W. H. Jung· 2 shared A. A. Magana· 1 shared A. Casadevall· 1 shared B. Black· 1 shared D. Croll· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

G. Hu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Glutathione metabolism impacts fungal virulence by modulating the redox environment

B. Black, L. B. Roque da Silva, G. Hu, X. Qu, D. F. Smith, A. A. Magana, L. C. Horianopoulos, M. Caza, R. Attarian, L. J. Foster, A. Casadevall, J. W. Kronstad

This study shows that glutathione metabolism in Cryptococcus neoformans affects virulence by modulating redox processes and melanin production in a murine infection model.

Nature Microbiology · Jul 2, 2024Peer-reviewedMicrobiology

The monothiol glutaredoxin Grx4 interacts with the Cryptococcus iron regulator Cir1 and regulates iron homeostasis and virulence in the Cryptococcus neoformans

R. Attarian, G. Hu, M. Caza, E. Sanchez-Leon, D. Croll, E. Do, H. Bach, T. Missall, J. Lodge, W. H. Jung, J. W. Kronstad

This study identifies Grx4 as a binding partner of Cir1 in Cryptococcus neoformans, showing that Grx4 regulates iron homeostasis and virulence through its interaction with Cir1.

bioRxiv · Jun 28, 2018Microbiology

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

M. Caza, G. Hu, E. D. Nielson, M. Cho, W. H. Jung, J. W. Kronstad

This study identifies Vps45's role in iron uptake, mitochondrial function, and virulence in Cryptococcus neoformans by analyzing a vps45 mutant's defects in trafficking, growth, and pathogenicity.

bioRxiv · Jun 27, 2018Microbiology

Role of clathrin-mediated endocytosis in the use of heme and hemoglobin by the fungal pathogen Cryptococcus neoformans

G. Bairwa, M. Caza, L. Horianopoulos, G. Hu, J. W. Kronstad

This study identifies clathrin-mediated endocytosis components essential for heme and hemoglobin uptake and virulence in Cryptococcus neoformans.

bioRxiv · Jun 20, 2018Microbiology